I am a
Home I AM A Search Login

Papers of the Week

2022 Jul 19

Int Orthop

Treatment of knee cartilage by cultured stem cells and three dimensional scaffold: a phase I/IIa clinical trial.


Neckar P, Potockova H, Branis J, Havlas V, Novotny T, Lykova D, Gujski J, Drahoradova I, Ruzickova K, Kaclova J, Skala P, Bauer PO
Int Orthop. 2022 Jul 19.
PMID: 35854056.


Damage of the knee cartilage is a common condition manifesting itself mainly by pain and/or swelling that may substantially reduce the quality of life while ultimately leading to osteoarthritis in affected patients. Here, we aimed to evaluate the safety and efficacy of cultured autologous bone marrow mesenchymal stem cells (BM-MSCs) attached to the 3D Chondrotissue® scaffold by autologous blood plasma coagulation (BiCure® ortho MSCp) in the treatment of knee cartilage defects.