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Papers of the Week

2022 Jun




Ketamine-Induced Syndrome of Inappropriate Antidiuretic Hormone Secretion and Hyponatremia.


Kumar K, Poonam F, Rani T, Prinka F, Ibeson CE, Nwosu I, Shetty V, Kalloo AN
Cureus. 2022 Jun; 14(6):e25931.
PMID: 35844311.


Ketamine is a dissociative anesthetic commonly used for the induction and maintenance of anesthesia and has a well-known role in analgesia. However, it also has the potential for addiction, which can lead to neurological, psychological, systemic, and biochemical consequences. In this case report, we are highlighting a rare case of a young Asian female with Ketamine addiction who presented with urinary complaints. The patient was found to have hyponatremia and laboratory tests were consistent with a syndrome of inappropriate antidiuretic hormone (SIADH) release in the absence of other causes.