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Papers of the Week
Genistein attenuates LPSinduced inflammatory injury of rat dorsal root ganglion neuron via downregulating HDAC6.
Abstract
Neuropathic pain (NP) is a chronic pain caused by somatosensory neuropathy or disease, and genistein (Gen) might be a potential drug for the treatment of NP. Therefore, this study aims to investigate the effect of Gen on lipopolysaccharide (LPS)-induced inflammatory injury of dorsal root ganglion neuron (DRGn) in rats and the possible molecular mechanism.