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Papers of the Week

Papers: 9 Jul 2022 - 15 Jul 2022

Human Studies


Rheumatol Adv Pract



Elevated highly sensitive C-reactive protein in fibromyalgia associates with symptom severity.


Zetterman T, Markkula R, Kalso E
Rheumatol Adv Pract. 2022; 6(2):rkac053.
PMID: 35832286.


Fibromyalgia (FM), a common pain syndrome, is thought to be a non-inflammatory, nociplastic condition, but evidence implicating neuroinflammation has been increasing. Systemic inflammation may be associated with more severe symptoms in some FM patients. We studied healthy controls and FM patients with and without systemic inflammation detectable using high-sensitivity CRP (hsCRP) measurement.