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Papers of the Week
Galcanezumab modulates Capsaicin-induced C-fiber reactivity.
Authors
PMID: 35796521.
Abstract
The vasodilatory calcitonin-gene related peptide (CGRP) is understood as pivotal mediator in migraine pathophysiology. Blocking CGRP with small molecules or monoclonal antibodies (CGRP-mAb) reduces migraine frequency. However, prescription of CGRP-mAbs is still regulated and possible predictive measures of therapeutic success would be useful.