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Papers of the Week

Papers: 2 Jul 2022 - 8 Jul 2022

2022 Jul 07

Ocul Immunol Inflamm

Neuropathic Corneal Pain as Debilitating Manifestation of LONG-COVID.


Woltsche J N, Horwath-Winter J, Dorn C, Boldin I, Steinwender G, Heidinger A, Woltsche N
Ocul Immunol Inflamm. 2022 Jul 07:1-3.
PMID: 35797498.


This report illustrates the case of a female patient suffering from severe ocular discomfort, tinnitus and ageusia, 7 months after a SARS-CoV-2 infection. The medical history implicated a diagnosis of LONG-COVID with ocular pain as the most debilitating symptom. In-vivo confocal microscopy revealed corneal microneuromas with hyperreflectivity and irregular enlargement of nerve endings in both eyes, which led to the diagnosis of neuropathic corneal pain. The aim of this report is to increase awareness that COVID-19 induced neuropathic pain can also occur in the cornea representing the human body's most richly innervated tissue.