A 5-year-old girl, the first-born child from a nonconsanguineous marriage, presented with multiple clear fluid-filled lesions present for 2 years, covering the body and when ruptured healed spontaneously with scarring. Sunlight aggravated the lesions. The child had had a hoarse voice since she was 1 year old. She also had developed multiple painful, nonhealing ulcers in mouth for 1 month duration she was 1 month old. There was no history of discoloration of urine or staining of undergarments, recurrent episodes of abdominal pain, headache, memory loss, or seizures. (. 2022;20:224-227).