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Papers of the Week

Papers: 2 Jul 2022 - 8 Jul 2022

Pharmacology/Drug Development

2022 Jul 01


Effectiveness of anti-CGRP monoclonal antibodies on central symptoms of migraine.


Iannone L F, De Cesaris F, Ferrari A, Benemei S, Fattori D, Chiarugi A
Cephalalgia. 2022 Jul 01:3331024221111526.
PMID: 35775208.


Clinical trials and observational studies with anti-calcitonin gene-related peptide antibodies poorly investigated their impact on migraine prodromal and accompanying symptoms. This information might help deciphering the biologics' pharmacodynamic and provide hints on migraine pathogenesis. Herein, we report the effects of erenumab, fremanezumab and galcanezumab on attack prodromal and accompanying symptoms and on neurological and psychiatric traits. .