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Papers of the Week

Papers: 25 Jun 2022 - 1 Jul 2022

Pharmacology/Drug Development

2022 Jun 23

Trends Pharmacol Sci

The calcium channel terminator: hasta la vista pain.


Harding EK, Zamponi GW
Trends Pharmacol Sci. 2022 Jun 23.
PMID: 35753846.


Chronic pain remains a major burden and is difficult to treat. N-type calcium channels may be a suitable therapeutic target for analgesics, and a new study from Colecraft and colleagues utilizes a clever new way to modulate their expression to achieve therapeutic benefits in preclinical models of neuropathic pain.