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Papers of the Week

Papers: 18 Jun 2022 - 24 Jun 2022

2022 Jun 20

BMC Neurosci



Frozen vein wrapping for chronic nerve constriction injury reduces sciatic nerve allodynia in a rat model.


Mukai M, Uchida K, Hirosawa N, Murakami K, Inoue G, Miyagi M, Shiga Y, Sekiguchi H, Inage K, Orita S, Suzuki T, Matsuura Y, Takaso M, Ohtori S
BMC Neurosci. 2022 Jun 20; 23(1):37.
PMID: 35725384.


Autologous vein wrapping (VW) is used in the treatment of recurrent chronic constriction neuropathy and traumatic peripheral nerve injury. However, use of autologous veins is limited by the inability to obtain longer veins of sufficient length for larger sites. Frozen allograft tissue has several advantages, including its availability for large grafts, avoidance of donor-site morbidity, and shorter operation time. Here, we investigated the effect of frozen vein wrapping (FVW) in Wistar rats as a model of sciatic nerve injury.