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Papers of the Week

Papers: 11 Jun 2022 - 17 Jun 2022

2022 Jun 13

Expert Opin Pharmacother

Advances in pharmacotherapy for the prophylactic treatment of resistant and refractory migraine.


Fitzek M, Raffaelli B, Reuter U
Expert Opin Pharmacother. 2022 Jun 13:1-11.
PMID: 35698795.


Refractory migraine is associated with low quality of life and great socioeconomic burden. Despite high need for effective, tolerable preventive therapies, there has been little research on potential therapeutic options. Monoclonal antibodies (mAbs) against Calcitonin Gene-Related Peptide (CGRP) are the first preventive therapeutic approach for migraine based on the underlying pathophysiology.