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Front Pharmacol


Application of Traditional Japanese Drug Jidabokuippo in a Modern Society.


Nakae H, Irie Y, Kitamura T, Okuyama M
Front Pharmacol. 2022; 13:853012.
PMID: 35677432.


Jidabokuippo (JDI) () has been used in Japan to alleviate contusion-induced swelling and pain since medieval times. This review investigated the effects of JDI on various symptoms in patients with trauma or static blood. The PubMed and Igaku Chuo Zasshi databases were searched until 24 December 2021. We summarize the benefits of applying JDI to inflammatory conditions, including bruises. JDI has been used to resolve blood stasis, regulate qi in trauma patients, and treat inflammatory swelling and pain caused by rheumatoid arthritis and cellulitis. As the adverse event rate associated with JDI is low (1.3%), JDI is considered a safe drug. JDI can be used to resolve blood stasis in trauma patients without adverse events associated with nonsteroidal anti-inflammatory drugs.