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Papers of the Week

Papers: 4 Jun 2022 - 10 Jun 2022

Pharmacology/Drug Development

2022 Jun 07


Reduced expression of inflammasome complex components in cluster headache.


Şahin E, Karaaslan Z, Şanlı E, Timirci Kahraman Ö, Ulusoy C, Kocasoy Orhan E, Ekizoğlu E, Küçükali C İ, Tüzün E, Baykan B
Headache. 2022 Jun 07.
PMID: 35670197.


The involvement of inflammation in the pathophysiology of cluster headache (CH) has been suggested, with a role implied for interleukin (IL)-1β. We aimed to measure peripheral blood expression levels of IL-1β-inducing systems, the inflammasome complex, and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling, and investigate their values as putative biomarkers in CH.