I am a
Home I AM A Search Login

Papers of the Week


Cancer Manag Res


Acute Mast Cell Leukemia Preceded by Malignant Mediastinal Germ Cell Tumor: A Case Report and Literature Review.


Wang H, Chen Y, Lin H, Ni W, Zhang Q, Lan J, Jin L
Cancer Manag Res. 2022; 14:1783-1794.
PMID: 35637940.


Mast cell leukemia (MCL) is a highly life-threatening and extremely rare subtype of systemic mastocytosis (SM). MCL often genetically contains one or more somatic mutations, particularly activating mutations of . This study reported on an acute MCL patient who had a rare phenotype and genetic mutants with a history of primary malignant mediastinal germ cell tumor (GCT).