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Papers of the Week


2022 Jun 01


Curr Opin Support Palliat Care


16


2

The pain conductor: brainstem modulation in acute and chronic pain.

Authors

Crawford LS, Boorman DC, Keay KA, Henderson LA
Curr Opin Support Palliat Care. 2022 Jun 01; 16(2):71-77.
PMID: 35639572.

Abstract

It is well established in experimental settings that brainstem circuits powerfully modulate the multidimensional experience of pain. This review summarizes current understanding of the roles of brainstem nuclei in modulating the intensity of pain, and how these circuits might be recruited therapeutically for pain relief in chronic and palliative settings.