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Papers of the Week

Papers: 28 May 2022 - 3 Jun 2022

2022 May 27

CNS Neurosci Ther

SUMOylation of Kir7.1 participates in neuropathic pain through regulating its membrane expression in spinal cord neurons.


Lv Y-Y, Wang H, Fan H-T, Xu T, Xin W-J, Guo R-X
CNS Neurosci Ther. 2022 May 27.
PMID: 35633059.


Potassium (K ) channels have been demonstrated to play a prominent involvement in nociceptive processing. Kir7.1, the newest members of the Kir channel family, has not been extensively studied in the CNS, and its function remains largely unknown. The present study investigated the role of spinal Kir7.1 in the development of pathological pain.