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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / MiR-223-3p alleviates trigeminal neuropathic pain in the male mouse by targeting MKNK2 and MAPK/ERK signaling.

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Papers: 21 May 2022 - 27 May 2022


Pharmacology/Drug Development


2022 May 24


Brain Behav


http://www.ncbi.nlm.nih.gov/pubmed/35608154?dopt=Abstract

MiR-223-3p alleviates trigeminal neuropathic pain in the male mouse by targeting MKNK2 and MAPK/ERK signaling.

Authors

MiR-223-3p alleviates trigeminal neuropathic pain in the male mouse by targeting MKNK2 and MAPK/ERK signaling.
Huang B, Guo S, Zhang Y, Lin P, Lin C, Chen M, Zhu S, Huang L, He J, Zhang L, Zheng Y, Wen Z
Brain Behav. 2022 May 24:e2634.
PMID: 35608154.

Abstract

Trigeminal neuralgia (TN) is a neuropathic pain that occurs in branches of the trigeminal nerve. MicroRNAs (miRNAs) have been considered key mediators of neuropathic pain. This study was aimed to elucidate the pathophysiological function and mechanisms of miR-223-3p in mouse models of TN.
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