I am a
Home I AM A Search Login

Papers of the Week

2022 Apr 16

Eur J Paediatr Neurol


Opioid analgesia and temperature regulation are associated with EEG background activity and MRI outcomes in neonates with mild-to-moderate hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia.


Mahdi Z, Marandyuk B, Desnous B, Liet A-S, Chowdhury R A, Birca V, Décarie J-C, Tremblay S, Lodygensky G A, Birca A, Pinchefsky EF, Dehaes M
Eur J Paediatr Neurol. 2022 Apr 16; 39:11-18.
PMID: 35598572.


Therapeutic hypothermia (TH) without sedation may lead to discomfort, which may be associated with adverse consequences in neonates with hypoxic-ischemic encephalopathy (HIE). The aim of this study was to assess the association between level of exposure to opioids and temperature, with electroencephalography (EEG) background activity post-TH and magnetic resonance imaging (MRI) brain injury in neonates with HIE.