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Papers of the Week
Complicated Clinical Course in Incipient Gigantism Due to Treatment-resistant Aryl Hydrocarbon Receptor-Interacting Protein-mutated Pediatric Somatotropinoma.
Abstract
Our objective was to describe the clinical course and treatment challenges in a very young patient with a pituitary adenoma due to a novel gene mutation, highlighting the limitations of somatostatin receptor immunohistochemistry to predict clinical responses to somatostatin analogs in acromegaly.