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Papers of the Week


2022


Int J Gen Med


15

Low-Dose Esketamine as an Adjuvant to Propofol Sedation for Same-Visit Bidirectional Endoscopy: Protocol for a Multicenter Randomized Controlled Trial.

Authors

Song N, Shan X-S, Yang Y, Zheng Z, Shi W-C, Yang X-Y, Li Y, Tan A-P, Liu H, Peng K, Ji F-H
Int J Gen Med. 2022; 15:4733-4740.
PMID: 35571286.

Abstract

Same-visit bidirectional endoscopy (esophagogastroduodenoscopy and colonoscopy) is widely performed under sedation. At present, the optimal sedation regimen remains unclear. This study aims to test the hypothesis that a low-dose esketamine added to propofol sedation reduces hemodynamic and respiratory adverse events in these procedures.