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Papers of the Week

2022 May 11

Int J Surg

Effects of neuromodulation on treatment of recurrent anal fissure: A systematic review.


Bananzadeh A, Sohooli M, Shamsi T, Darabi M, Shahriarirad R, Shekouhi R
Int J Surg. 2022 May 11:106661.
PMID: 35568308.


Anal fissure is a linear tear in the distal anoderm most frequently occurring in the posterior midline. Lateral internal sphincterotomy is considered the gold standard for the treatment of this condition. To this date, several pharmacological and neuromodulatory therapies have been tried out as alternative non-invasive treatments for anal fissures, however, the efficacy of some of these methods remains to be understood.