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Papers of the Week

2022 May 02

Arch Orthop Trauma Surg

Preemptive multimodal analgesia and post-operative pain outcomes in total hip and total knee arthroplasty.


Passias BJ, Johnson DB, Schuette HB, Secic M, Heilbronner B, Hyland SJ, Sager A
Arch Orthop Trauma Surg. 2022 May 02.
PMID: 35499774.


Use of multimodal analgesia (MMA) prior to orthopedic surgery has been adopted by many practitioners as a strategy to minimize use of opioid medications. The purpose of this investigation was to quantify the effect of a preemptive three-drug regimen (acetaminophen, celecoxib, and gabapentin) in terms of post-operative opioid consumption and pain control in the field of total joint arthroplasty.