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Papers of the Week

2022 Apr

Int J Spine Surg



Anterior Cervical Discectomy and Fusion With a No-Profile Integrated Fixation Allograft Device: An In Vitro Biomechanical Analysis and Clinical Case Series.


Salari N, Konz G, Ferry C, Gandhi A, Freeman A, Davis R, Yeung C
Int J Spine Surg. 2022 Apr; 16(2):247-255.
PMID: 35444033.


No-profile anterior cervical discectomy and fusion (ACDF) devices are commonplace in spinal surgery. Contained within the intervertebral margins, these devices diminish risks associated with anterior cervical plating, while also marginalizing cage migration and subsidence. However, these devices have been limited in their scope of implant material. Accordingly, a no-profile ACDF (npACDF) device supporting a machined allograft implant body with a connected load-sharing fixation interface was developed. However, it is not established in the literature whether the device supports early mechanical stability and subsequent boney fusion. The objective of this study was to assess this device in both the clinical and preclinical settings.