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Papers of the Week


2022


Front Psychiatry


13

Cognitive Dysfunction of Chikungunya Virus Infection in Older Adults.

Authors

Peixoto V GMNP, Azevedo JP, Luz KG, Almondes KM
Front Psychiatry. 2022; 13:823218.
PMID: 35449568.

Abstract

Chikungunya fever is a disabling articular disease caused by chikungunya virus (CHIKV). In the past decade it has affected millions of people across America, Africa, Asia, and Europe, turning this infection into a public health concern. The acute phase of chikungunya infection is usually self-limiting, characterized by severe arthralgia, fever, chills, myalgia, headache, and rash. CHIKV neurovirulence is evident and seems to be higher among elders. Considering their susceptibility to cognitive decline and dementia, the aim of our study was to investigate whether CHIKV infection might cause long-term cognitive impairment in aged people.