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Papers of the Week

Papers: 16 Apr 2022 - 22 Apr 2022

Pharmacology/Drug Development

2022 Apr 20

Expert Opin Ther Pat

P2X Receptor Antagonists and their Potential as Therapeutics: a patent review (2010 – 2021).


Dane C, Stokes L, Jorgensen WT
Expert Opin Ther Pat. 2022 Apr 20.
PMID: 35443137.


: Purinergic receptors play a critical role in neurotransmission, and modulation of complex physiological functions. As such, they have been implicated in numerous disease states including chronic pain, inflammation, autoimmune disease, and cancer. The past decade has seen substantial progress in the design of novel chemical compounds that act on the P2X class of receptors and warrants an updated review of this field.