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Papers of the Week


2022 Apr 11


Knee


36

Transcatheter arterial embolization of abnormal neovessels in a swine model of knee arthritis.

Authors

Kamisako A, Ikoma A, Koike M, Makitani K, Fukuda K, Higashino N, Shibuya M, Okuno Y, Minamiguchi H, Sonomura T
Knee. 2022 Apr 11; 36:20-26.
PMID: 35421700.

Abstract

In recent years, transcatheter arterial embolization (TAE) using imipenem/cilastatin (IPM/CS) has attracted attention as a treatment for relieving osteoarthritis (OA) pain. However, IPM/CS is not approved by Japanese medical insurance for use as an embolic material. Therefore, it is necessary to develop new embolic materials for TAE to relieve OA pain. The purpose of this study was to develop a swine model of knee arthritis and embolize abnormal neovessels (ANs) using two different embolic materials. We compared the embolic effects and tissue damage in knees.