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Papers of the Week


2022


Front Med (Lausanne)


9

Leprosy Reactions and Neuropathic Pain in Pure Neural Leprosy in a Reference Center in Rio de Janeiro – Brazil.

Authors

Pitta I J R, Hacker M A, Vital R T, Andrade L R, Spitz C N, Sales A M, Antunes S L G, Sarno E N, Jardim M R
Front Med (Lausanne). 2022; 9:865485.
PMID: 35402428.

Abstract

Leprosy reactions are complications that can occur before, during, or after multidrug therapy (MDT) and are considered a major cause of nerve damage. Neuritis is an inflammatory process that causes nerve function impairment associated with pain and tenderness along the nerve. Neuritis can be found in both type 1 and type 2 reactions and may also be the sole manifestation of a leprosy reaction. The objective of this study is to describe the incidence of leprosy reactions and its association with neuropathic pain in pure neural leprosy (PNL) patients.