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Papers of the Week

2022 Apr 08

BMJ Case Rep



Post-COVID-19 syndrome: persistent neuroimaging changes and symptoms 9 months after initial infection.


Grach SL, Ganesh R, Messina SA, Hurt RT
BMJ Case Rep. 2022 Apr 08; 15(4).
PMID: 35396239.


A previously healthy and active middle-aged woman acquired COVID-19 as an occupational exposure with subsequent persistent post-COVID-19 symptoms including headache, dyspnoea on exertion, chest pressure, tachycardia, anosmia, parosmia, persistent myalgia, vertigo, cognitive decline and fatigue. She presented to a tertiary medical centre for further evaluation after 9 months of persistent symptoms and had a largely unremarkable workup with the exception of a persistently elevated monocyte chemoattractant protein 1, blunted cardiovagal response and non-specific scattered areas of low-level hypometabolism at the bilateral frontal, left precuneus, occipital and parietal regions on PET scan.