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Papers of the Week

2022 Mar 06

Zhonghua Yu Fang Yi Xue Za Zhi



[Research progress on the incidence and economic burden of herpes zoster disease in immunocompromised population].


Yang YY, Fu CX
Zhonghua Yu Fang Yi Xue Za Zhi. 2022 Mar 06; 56(3):386-390.
PMID: 35381664.


With the increase of age or the impairment of immune function, the specific cellular immune level against varicella zoster virus (VZV) in the body decreases, and the latent VZV in the ganglion can be reactivated to cause herpes zoster (HZ). HZ and its main complication postherpetic neuralgia (PHN) can seriously affect the quality of life of patients. The immunocompromised (IC) population is more prone to HZ than the immunocompetent population due to diseases and therapeutic drugs. This paper reviews the incidence, risk factor and economic burden of HZ in IC population with special health status, to provide ideas for research and adjustment of immunization strategies in the future.