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Papers of the Week


2022 Apr 05


Minerva Anestesiol

Efficacy of intravenous versus intraperitoneal lidocaine for postoperative analgesia in laparoscopic cholecystectomy: a randomized, double-blind, placebo-controlled trial.

Authors

Lapisatepun W, Nitayamekin A, Leurcharusamee P, Pianngarn I, Maykanggoon K, Chotirosniramit A, Junrungsee S, Sandhu T, Ko-Iam W, Lapisatepun W
Minerva Anestesiol. 2022 Apr 05.
PMID: 35381840.

Abstract

Laparoscopic cholecystectomy (LC) has become the gold standard for gallbladder removal due to the low degree of invasiveness. However, postoperative pain still persists. Local anesthetics provide analgesia, reduce opioid consumption, and accelerate the return of bowel activity with a rare incidence of toxicity. However, it is still inconclusive to verify the more superior route of administration. This study aimed to compare the efficacy of intravenous lidocaine infusion, intraperitoneal lidocaine instillation, and placebo in reducing postoperative analgesia.