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Papers of the Week

Papers: 2 Apr 2022 - 8 Apr 2022

2022 Apr 06

Bioelectron Med



Anatomical differences in nociceptor neurons sensitivity.


Crosson T, Talbot S
Bioelectron Med. 2022 Apr 06; 8(1):7.
PMID: 35382899.


Dorsal Root Ganglia (DRG) neurons are derived from the neural crest and mainly innervate the skin, while Jugular Nodose Complex (JNC) neurons originate from the placode and innervate internal organs. These ganglia are composed of highly heterogeneous groups of neurons aimed at assessing and preserving homeostasis. Among other subtypes, nociceptor neurons are specialized in sensing and responding to environmental dangers. As form typically follows function, we hypothesized that JNC and DRG neurons would be phenotypically and transcriptomically different.