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Papers of the Week

2022 Mar 23

Am J Emerg Med


Analgesic efficacy of nitrous oxide in adults in the emergency department: A meta-analysis of randomized controlled trials.


Xing Y, Zhou L, Yu J, Wang Z, Ding Z, Xie C, Li Y, Wang F, Tang L
Am J Emerg Med. 2022 Mar 23; 56:92-99.
PMID: 35367685.


Nitrous oxide (NO) has a rapidly analgesic effect, but evidence regarding its role in managing pain in adults in the emergency department (ED) is conflicting. The purpose of this meta-analysis is to investigate the analgesic efficacy and safety of NO in adults in ED.