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Papers of the Week

2022 Apr 04

Cardiovasc Ultrasound



Cardiac microstructural alterations in immune-inflammatory myocardial disease: a retrospective case-control study.


Kwan AC, Salto G, Nguyen T-T, Kim EH, Luong E, Hiremath P, Ouyang D, Ebinger JE, Li D, Berman DS, Kittleson MM, Kobashigawa JA, Patel JK, Cheng S
Cardiovasc Ultrasound. 2022 Apr 04; 20(1):9.
PMID: 35369883.


Immune-inflammatory myocardial disease contributes to multiple chronic cardiac processes, but access to non-invasive screening is limited. We have previously developed a method of echocardiographic texture analysis, called the high-spectrum signal intensity coefficient (HS-SIC) which assesses myocardial microstructure and previously associated with myocardial fibrosis. We aimed to determine whether this echocardiographic texture analysis of cardiac microstructure can identify inflammatory cardiac disease in the clinical setting.