Cerebral venous sinus thrombosis (CVST) is a rare type of cerebrovascular disease that affects mainly young to middle-aged adults. The main clinical presentation of CVST includes progressive headache, focal neurological deficit, disturbance of conscious level, and epileptic seizures, which can occur early or late in the disease process. Generalized seizure has been recognised as the most common seizure subtype among patients with CVST and epileptic seizures. Epilepsia partialis continua (EPC), a subclass of focal motor status epilepticus, has rarely been reported as the initial presenting feature of CVST. Here, an encounter of CVST with an isolated initial presentation of EPC involving the right hand is presented. The initial discordant clinical and radiological findings prompted further investigations that revealed patchy venous infarction along the precentral gyrus that attributed to the occurrence of EPC.