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Papers of the Week


2020 Dec 31


Kidney360


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12

Combination Hydralazine and Isosorbide Dinitrate in Dialysis-Dependent ESRD (HIDE): A Randomized, Placebo-Controlled, Pilot Trial.

Authors

Charytan DM, Hsu JY, Mc Causland FR, Waikar SS, Ikizler AT, Raj DS, Landis RJ, Mehrotra R, Williams M, DiCarli M, Skali H, Kimmel PL, Kliger AS, Dember LM
Kidney360. 2020 Dec 31; 1(12):1380-1389.
PMID: 35372900.

Abstract

Combination therapy with isosorbide dinitrate (ISD) and hydralazine (HY) reduces heart failure mortality. The safety and tolerability in individuals requiring maintenance hemodialysis (HD) is unknown.