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Papers of the Week

2022 Apr 01

Korean J Pain



Antinociceptive, anti-inflammatory, and cytotoxic properties of essential oil, rich with β-caryophyllene and β-caryophyllene oxide.


Moghrovyan A, Parseghyan L, Sevoyan G, Darbinyan A, Sahakyan N, Gaboyan M, Karabekian Z, Voskanyan A
Korean J Pain. 2022 Apr 01; 35(2):140-151.
PMID: 35354677.


Essential oils are of great interest for their analgesic and anti-inflammatory properties. We aimed to study the content of the essential oil of the Origanum vulgare of the Armenian highlands (OVA) in different periods of vegetation and to investigate its antinociceptive and anti-inflammatory effects in mice (in vivo) and cytotoxic action in cultured cells (in vitro). OVA essential oil was extracted from fresh plant material by hydro-distillation.