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Front Immunol


Two CIDP Variants Patients With Anti-Caspr1 Antibodies in South China.


Li C, Zheng H, Yuan C, Li Y, Hu Y, Jiang H
Front Immunol. 2022; 13:844036.
PMID: 35359983.


Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is considered an immune-mediated heterogeneous disease that involves both cellular and humoral immunity. The advent of the new concept of node-paranodopathy in recent years has boosted the identification of more antibody-positive CIDP variants patients. Cases of Caspr1 autoantibodies are the least common. Here, we reported two patients with Caspr1 autoantibodies and summarized their clinical features and treatment responses.