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Papers of the Week

2022 Mar 27

J Med Case Rep



Omeprazole-induced galactorrhea in kidney transplant patients-a case report.


Dorji C, Robin F A, Na-Bangchang K
J Med Case Rep. 2022 Mar 27; 16(1):121.
PMID: 35339194.


Omeprazole belongs to the pharmacological classifications of proton pump inhibitors and is a widely used medicine. All proton pump inhibitors have a common mechanism of action and are prodrugs that require activation in an acidic environment. Omeprazole is extensively metabolized in the liver by cytochrome 2C19 and cytochrome 3A4, which are responsible for drug interactions. Omeprazole-induced galactorrhea is a rare adverse event of drug metabolism and is often underreported.