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Papers of the Week

2022 Apr

Case Rep Womens Health


Stevens-Johnson syndrome with vulvar involvement: A case report and literature review.


Hollingsworth J, Park SU, Bhagavathi V, Green A, Philips N
Case Rep Womens Health. 2022 Apr; 34:e00404.
PMID: 35340779.


Stevens-Johnson syndrome is a rare, life-threatening mucocutaneous condition causing necrosis and detachment of the epidermis. Vulvovaginal involvement, seen in up to 70% of affected women, can lead to painful chronic conditions such as adenosis, hematocolpos, and chronic pelvic pain. To date, there is no consensus regarding the optimal treatment of vulvovaginal involvement. In this case report, one case of Stevens-Johnson syndrome with vulvar and vaginal involvement is described, and the treatment options for this rare condition are reviewed.