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Papers of the Week

2022 Mar 24

J Perioper Pract

Single-dose premedication enhances multimodal analgesia after knee arthroplasty.


Kardash K, Harvey E, Payne S, Yang S S
J Perioper Pract. 2022 Mar 24:17504589211049292.
PMID: 35322698.


With the current trend to reduce postoperative opioid use to enhance recovery and address perioperative opioid addiction concerns, the challenge of managing pain after total knee arthroplasty has increased. This study examined the effect of adding a preoperative medication regime to a multimodal postoperative analgesia protocol that included regional anaesthesia.