I am a
Home I AM A Search Login

Papers of the Week

2022 Mar 24

Acta Anaesthesiol Scand

Perioperative prevention of persistent pain after total hip and knee arthroplasty – protocol for two systematic reviews.


Laigaard J, Karlsen A, Maagaard M, Rosenberg L K, Creutzburg A, Lunn T H, Mathiesen O, Overgaard S
Acta Anaesthesiol Scand. 2022 Mar 24.
PMID: 35325472.


Between 9 and 20% of patients experience moderate to severe persistent postoperative pain after total hip or knee arthroplasty. Severe immediate postoperative pain limits rehabilitation and is associated with development of persistent postoperative pain. Therefore, perioperative analgesic and physiotherapeutic interventions are of interest to reduce persistent pain. In two systematic reviews with identical methodology, we aim to investigate the effects of a) perioperative analgesic interventions and b) physiotherapeutic interventions in reducing persistent pain after total hip and knee arthroplasty.