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Papers of the Week

2022 Mar 13

J Clin Med



Neurological Presentation of Giant Pituitary Tumour Apoplexy: Case Report and Literature Review of a Rare but Life-Threatening Condition.


Puglisi V, Morini E, Biasini F, Vinciguerra L, Lanza G, Bramanti P
J Clin Med. 2022 Mar 13; 11(6).
PMID: 35329907.


Giant pituitary adenomas are benign intracranial tumours with a diameter ≥4 cm. Even if hormonally non-functional, they may still cause local extension, leading to symptoms that include mostly gland dysfunction, mass effects, and, much less frequently, apoplexy due to haemorrhage or infarction. Neurological presentation of giant pituitary tumour apoplexy is even more rare and has not been systematically reviewed.