Browse by Audience
Skip to content
Papers of the Week
Atogepant – an orally-administered CGRP antagonist – attenuates activation of meningeal nociceptors by CSD.
Abstract
This study investigated the mechanism of action of atogepant, a small-molecule CGRP receptor antagonist recently approved for the preventive treatment of episodic migraine, by assessing its effect on activation of mechanosensitive C- and Aδ-meningeal nociceptors following cortical spreading depression.