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Papers of the Week

Papers: 19 Mar 2022 - 25 Mar 2022

Pharmacology/Drug Development

2022 Mar 19

J Nanobiotechnology



Triamcinolone acetonide-loaded nanoparticles encapsulated by CD90 MCSs-derived microvesicles drive anti-inflammatory properties and promote cartilage regeneration after osteoarthritis.


Osteoarthritis (OA) is a highly prevalent human degenerative joint disorder that has long plagued patients. Glucocorticoid injection into the intra-articular (IA) cavity provides potential short-term analgesia and anti-inflammatory effects, but long-term IA injections cause loss of cartilage. Synovial mesenchymal stem cells (MSCs) reportedly promote cartilage proliferation and increase cartilage content.