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Papers of the Week

Papers: 19 Mar 2022 - 25 Mar 2022

Human Studies

2022 Mar 21

Depress Anxiety

Physical multimorbidity and depression: A mediation analysis of influential factors among 34,129 adults aged ≥50 years from low- and middle-income countries.


Smith L, Shin J I, Butler L, Barnett Y, Oh H, Jacob L, Kostev K, Veronese N, Soysal P, Tully M, López Sánchez GF, Koyanagi A
Depress Anxiety. 2022 Mar 21.
PMID: 35312125.


There is a scarcity of literature on the association between physical multimorbidity (i.e., ≥2 chronic physical conditions) and depression among older adults, especially from low- and middle-income countries (LMICs). In addition, the mediators in this association are largely unknown. Therefore, we aimed to examine this association among adults aged ≥50 years from six LMICs (China, Ghana, India, Mexico, Russia, and South Africa), and to identify potential mediators.