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Papers of the Week

2022 Mar 21

Hum Psychopharmacol

Efficacy of tiapride in the treatment of psychiatric disorders: A systematic review.


Zangani C, Giordano B, Stein H-C, Bonora S, Ostinelli E G, D'Agostino A
Hum Psychopharmacol. 2022 Mar 21:e2842.
PMID: 35313032.


Tiapride is an atypical antipsychotic used to treat alcohol withdrawal, aggressiveness and agitation, headache, dyskinesias, tic and Tourette's disorder. More recently, it has been proposed for the treatment of delirium and agitation in hospitalised patients with COVID-19. Although its safety profile makes it suitable for use in vulnerable populations, the use of tiapride for psychiatric disorders is limited. This work aims to systematically review the available evidence on the efficacy and tolerability of tiapride in individuals with a psychiatric disorder.