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Papers of the Week

2022 Mar 19

J Med Case Rep



Oxaliplatin-induced thrombotic microangiopathy: a case report.


Saad R, Hannun A, Temraz S, Finianos A, Zeenny RM
J Med Case Rep. 2022 Mar 19; 16(1):110.
PMID: 35303936.


Oxaliplatin-based chemotherapy represents a standard of care in the treatment of metastatic colorectal cancer. We report a rare case of fulminant oxaliplatin-induced thrombotic microangiopathy, clinically suggestive of hemolytic-uremic syndrome, occurring in a female patient with a prolonged history of exposure to oxaliplatin for the treatment of metastatic colon cancer.