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Papers of the Week

2022 Mar 17

Pain Manag

Intrathecal neurolysis for the management of refractory pain in a patient with terminal oncological disease: case report.


Rangel Jaimes G W, Ortega Agón K A, Cediel Carrillo X J
Pain Manag. 2022 Mar 17.
PMID: 35297268.


We report on the successful treatment of refractory cancer pain by intrathecal neurolysis using 96% absolute alcohol. A female patient with colorectal adenocarcinoma with metastases to the sacral bones, the patient had severe pain refractory to pharmacological and interventional treatment. Intrathecal neurolytic block at the L5-S1 intervertebral space was performed, she reported a significant improvement in her pain and decreased opioid use. The patient did not show deterioration of neurological functions after the procedure or associated complications, and outpatient treatment continued with a home medicine program. She remained comfortable until her death 6 weeks later. Considering that this is an accessible and cost-effective procedure, it could be a helpful alternative for the management of patients with refractory pain in the terminal stage.