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Papers of the Week

Papers: 12 Mar 2022 - 18 Mar 2022

Pharmacology/Drug Development


Front Neurol


Acute Medication Use in Patients With Migraine Treated With Monoclonal Antibodies Acting on the CGRP Pathway: Results From a Multicenter Study and Proposal of a New Index.


Sette L, Caponnetto V, Ornello R, Nežádal T, Čtrnáctá D, Šípková J, Matoušová Z, Sacco S
Front Neurol. 2022; 13:846717.
PMID: 35295829.


Assessing the impact of migraine preventive treatments on acute medication consumption is important in clinical evaluation. The number of acute medication intakes per each monthly migraine day (MMD) could provide insights on migraine burden and represent a new proxy of treatment effectiveness in clinical trials and real-life studies. We evaluated the effect of monoclonal antibodies acting on calcitonin gene-related peptide (CGRP) pathway on the consumption of migraine acute medication in real-life.