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Papers of the Week


2022 Mar 14


Trials


23


1

OPAL: a randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain-a statistical analysis plan.

Authors

Jones C M, Lin C-W C, Day RO, Koes BW, Latimer J, Maher CG, McLachlan A, Billot L
Trials. 2022 Mar 14; 23(1):212.
PMID: 35287698.

Abstract

Low back and neck pain are a leading cause of disease burden globally. Opioids are recommended in guidelines for acute low back and neck pain; however, there is a lack of compelling efficacy data to support this.